Richard Hodes, MD (NIA)



NIH’s Health Care Systems Research Collaboratory is intended to improve the way clinical trials are conducted by creating a new infrastructure for collaborative research, and particularly pragmatic clinical trials. The ultimate goal is to ensure that healthcare providers and patients can make decisions based on the best available clinical evidence. 

The NIH Collaboratory also supports the design and rapid execution of several high-impact Pragmatic Clinical Trial Demonstration Projects that address questions of major public health importance and engage health care delivery systems in research partnerships. The NIH Collaboratory includes a Coordinating Center that provides national leadership and technical expertise in all aspects of research with health care systems.





  • Duke Clinical Research Institute

  • Center for Medical Technology Policy

  • Harvard Pilgrim Health Care Institute (HCSRN member)

  • Group Health Research Institute (HCSRN member)

  • Johns Hopkins Berman Institute of Bioethics



Several of the NIH Collaboratory demonstration projects are led by or partner with HCSRN research centers and health systems.



  • Knowledge repository and The Living Textbook – The NIH Collaboratory Coordinating Center offers collected documentation, guidance, and other resources on a variety of aspects of research with health systems.

  • Grand Rounds webinars– Join the NIH Collaboratory Coordinating Center for Friday “Grand Rounds” webinars or view archived webinars.